| TI: |
Title
Potential of Quantity of Coronary Artery Calcification to Identify;
New Risk Factors for Asymptomatic Atherosclerosis |
| AU: |
Author
MAHER, JE; RAZ, JA; BIELAK, LF; SHEEDY, PF; SCHWARTZ ET AL., RS
|
| SO: |
Source
American Journal of Epidemiology, vol. 144, no. 10, pp. 943-953,
November 15, 1996 |
| AB: |
Abstract
Researchers examined the relations between established coronary
artery disease (CAD) factors and quantity of coronary artery calcification
(CAC) in three arterial locations using generalized linear mixed
models. The variability was estimated in quantity of CAC explained
by established CAD risk factors and the variability due to noise
or artifact in the measure. The community-based sample included
740 asymptomatic adults (378 women) aged 20-59 yr. without hypertension
or diabetes. Participants were recruited from Rochester, Minnesota,
between 1990 and 1994. Quantity of CAC in three arterial locations
was detected noninvasively by electron beam computed tomography.
Sex, arterial location, age, body size, blood pressure, lipid
metabolism, and smoking were significantly associated with quantity
of CAC. Age was more strongly associated with quantity of CAC
in the left than that in the right coronary or circumflex arterial
locations. In each sex, risk factors together explained less than
40% of the variability in quantity of CAC. Noise and artifact
in the measure accounted for only a small proportion of unexplained
variability. |
| PY: |
Publication Year
1996 |
| DE: |
Descriptors
ATHEROSCLEROSIS; HEART DISEASE; CORONARY ARTERY DISEASE; CORONARY
ARTERY CALCIFICATION; RISK FACTORS; TOMOGRAPHY |
| SF: |
Subfile
Biology Digest |
| AN: |
Accession Number
96/97-1948 |
